Selective nanosensor based on folic acid imprinted nanostructures
نویسندگان
چکیده
Folic acid, which provides the transfer of single carbon atoms in synthesis reactions and metabolic cycles metabolism, is very important for metabolism. acid also plays an role nucleotide methylation reactions. There are many disorders caused by defective folic metabolism lack acid. Today, innovative, cost-effective methods needed to develop determination methods. The main objective this study development surface-printed electrodes (SPCE) modified with imprinted nanostructures (FA-Imp-poly(MPTS-rGO-co-NAT), will be used first time commercially human blood serum. For purpose, has been carried out characterized FTIR, SEM-EDS, AFM. Then, a new chemically nanosensor was fabricated using nanostructures. Differential pulse voltammetry (DPV) circular (CV) were as electrochemical FA-imprinted-nanosensor studies. Measurements differential performed at application speed 0.005 volts per second potential range ?0.4 0.6 volts. As result voltammetric method, idea about surface obtained voltammograms obtained. detection limit (LOD) developed 7.54 ng/mL (LOQ) 25.14 ng/mL. FA analytical (10 20 ng/mL) added commercial synthetic serum samples standard adding method RSD values 0.092% 0.734% found DPV technique measurements respectively. This manuscript demonstrated novel, simple, selective, rapid FAimprinted- determining biological samples.
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ژورنال
عنوان ژورنال: Turkish Journal of Chemistry
سال: 2022
ISSN: ['1300-0527', '1303-6130']
DOI: https://doi.org/10.55730/1300-0527.3428